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WWW.nice.org.uk/nicemedia/pdf /GG017 nice guideline.pdf (accessedMay2010 2

6 Despite these distinctions, protocols for treatment, assessment, and referral remain poorly standardized

Senotherapeutic drugs can be divided into two main groups: senolytics and senomorphics [97]

Verdict at a Glance Oveporexton (TAK-861) is the clear winner on scientific evidence, having demonstrated statistically significant efficacy across multiple Phase 3 trials for narcolepsy type 1, with a well-characterized mechanism targeting the orexin receptor 2