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IshikawaFYoshidaSSaitoYHijikataAKitamuraHTanakaSet alChemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region

Importantly, the authors have also demonstrated that inhibition of glutathione synthesis using BSO and Gclc siRNA knockdown were similarly decreasing cellular GSH levels, increasing oxidative stress and affecting the vitamin D metabolism (50)

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