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Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors

Perxs Perich M, Palma-Florez S, Sol C, Goberna-Ferrn S, Samitier J, Gmez-Romero P, Mir M, Lagunas A

Human evidence is limited to a handful of small studies for BPC-157 and even less for the rest, long-term safety data doesnt exist, and the compounds sit in a regulatory grey zone that may shift through 2026

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