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[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Binsfeld M, Muller J, Lamour V, De Veirman K, De Raeve H, Bellahcene A, et al

Additional mechanisms were demonstrated to play a role in the pathogenesis of lipedema including increased vascular permeability and damage (microangiopathy), excessive lipid peroxidation, and disturbances in adipocyte metabolism and cytokine production [9,10]

doi: 10.1016/j.phrs.2021.105853 81

D-qY: Conceptualization, Writing review & editing

However, the inhibition of p-AKT by AZD5363 induced c-MET phosphorylation and the levels of p-c-MET remained unchanged when the cells were treated with TGF- in the presence of AZD5363 (Fig