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Am J Physiol Endocrinol Metab 296:E13541362 MacDonald MJ, Marshall LK (2001) Survey of normal appearing mouse strain which lacks malic enzyme and Nad+-linked glycerol phosphate dehydrogenase: normal pancreatic beta cell function, but abnormal metabolite pattern in skeletal muscle

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Echinocyte formation is typically reversible and can result from alterations in membrane lipid composition, oxidative stress or exposure to certain plasma factors