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The main ones in the diet can be found in proteins, such as beef, fish, and poultry

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These drugs include monoclonal antibodies targeting Wnts and FZD receptors, molecules inhibiting their secretion and interaction, and small molecule inhibitors that stabilize the -catenin destruction complex and block the binding of -catenin to specific transcription co-activators ( Table 1 )

On the other hand, the subsequent antioxidant protection can be achieved by regulating the Nrf2/HO-1 signaling pathway ( The hepatoprotective effects of NF-B and Nrf2 have been demonstrated in BLM-treated animals

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