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Targeting different sites involved in Caspase interactions with XIAP using small-molecule chemical inhibitors induces synergistic apoptosis of leukemia cells

Components synergy between stilbenes and emodin derivatives contributes to hepatotoxicity induced by by Polygonum multiflorum

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[PubMed Citation] To develop management guidelines for the treatment of anaphylactoid reactions to intravenous N-acetylcysteine (NAC) and to assess the safety of restarting the infusion after a reaction

This cascade of metabolic dysregulation not only directly induces the phenotype switching of PASMCs from a contractile to a highly proliferative and migratory synthetic phenotype [132] but also causes significant medial wall thickening, ultimately driving PH disease progression