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[DOI] [PMC free article] [PubMed] [Google Scholar] 248

A second-generation tracer [ 11 C] Kln83 with improved selectivity was subsequently designed and is now used in clinical settings 562,563

Consistently, when cells were subjected to cystine starvation in the presence of 6-diazo-5-oxo-L-norleucine (DON, a selective GGT inhibitor), there was a markedly higher accumulation of extracellular GSH (Fig