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The American Journal of Physiology 272 (5 Pt 1), C1499C1506

The pathogenesis of atherosclerosis, one of the most prevalent cardiovascular diseases, is linked to lipid metabolism

[5] The consequences of this bond are large

In this 10% of patients, 6-MP and another related chemical (6-thioguanine or 6-TG) accumulate and are toxic to the bone marrow where blood cells are produced