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This intersection positions NETosis not merely as an antimicrobial strategy but as a cytotoxic effector mechanism driving sterile inflammation, endothelial dysfunction, and thrombo-inflammatory propagation in PCOS and related metabolic disorders

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doi: 10.1002/14651858.CD006316.pub3 53 SumitaniMTochinoYKamimoriTFujiwaraHFujikawaT

Yet the evidence base on whether the loss of skeletal muscle (or other body composition components) is beyond what would be expected with weight loss without GLP-1 agonist drugs is largely based on anecdotes, conjectures, and studies with weak measurement and weak designs

A cluster of families has been identified in the southeastern USA, suggesting a possible founder effect 197