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Description

In rodent brain, galactosylcholesterol is derived via the same glucosyltransferases from galactosylceramide

Fermino, M

PLoS ONE, 8(7)

On the one hand, this promotes the release of pro-inflammatory factors including IL-6 and TNF- (48, 49)

From a structureactivity relationship (SAR) perspective, immunostimulatory PDEVs are associated with cargo that activate pro-inflammatory signaling pathways such as MAPK and NF-B