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[9] Research [edit] Because thiamine deficiency causes problems with memory and other cognitive functions, thiamine and analogs like sulbutiamine have been studied in clinical trials in the 1980s and 1990s for age-associated cognitive decline

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The investigators reported that Epithalon induced telomerase activity in cultures that were previously telomerase-negative, with corresponding increases in telomere length, and concluded that the peptide may extend cell-population lifespan through anti-senescence activity [1]