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For example in older mice, damage in the antioxidant system occurs, and is associated with lower mitochondrial GSH (Shi et al., 2010) and superoxide dismutase activities in the neocortex (Wang et al., 2015), as well as decreased GSH/GSSG ratio in the cortex, striatum, hippocampus and cerebellum (Rebrin et al., 2007)

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Therefore, we conclude that RT is able to reliably measure the intracellular GSH levels

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Wang et al., 2004