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In EBV-positive but p53-null H1299A cells, MNNG loses its ability to induce EBV reactivation suggesting p53 expression is critical for MNNG-induced EBV reactivation (Figure 5C)

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Study design This two-arm double-blind randomized placebo-controlled parallel study with a 1:1 allocation was performed at Arkansas Childrens Research Institute (Little Rock, AR, USA) from 4 June 2012 to 22 November 2013

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