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This is a common concern for patients considering GLP-1 receptor agonists like semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro)

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Injection Site Safety: Absorption, Rotation, and Lipohypertrophy Subcutaneous absorption of GLP-1 medications varies slightly by injection site, though all FDA-approved regions provide therapeutically equivalent bioavailability when properly administered