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Eckenroth et al., 2006

M., Aaron, J

However, as suggested by a previous MR study [23], uric acid is downstream of l-carnitine, i.e., a mediator, so we did not exclude it as an invalid genetic instrument

To date, several key ferroptosis-related targetssuch as GPX4, ACSL4, FTH1, and SLC7A11and upstream regulatory pathways including Nrf2, TLR4, and STING, have been identified