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Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease

In that sense, the advocates of this form of absolutism resemble those who let the opera continue while a man in the audience lay unconscious

For solutions prone to oxidation, purging vials with nitrogen or argon can help maintain stability

To substantiate this study, we transiently transfected HEK293T cells with constructs expressing N0362-GFP, C0362-GFP, C0362 C412A -GFP (a point mutant in which Cys-412 was replaced with alanine) or GFP alone (control) and found that N0362-GFP was mainly localized around the nuclear membrane or around the peripheral of the nucleus while C0362-GFP led to cell shrinkage, rounding up, and lysis, indicating that C0362 is toxic