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doi: 10.5483/BMBRep.2023-0030 129

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PBT2 acts by modulating metalprotein interaction networks, thereby restoring ironcopper balance in the brain and indirectly reducing A deposition, offering dual-target therapeutic potential (Chen L

doi: 10.3389/fmicb.2026.1787284 Received 15 January 2026 Revised 23 February 2026 Accepted 25 February 2026 Published 17 March 2026 Volume 17 - 2026 Edited by Charalampia Amerikanou, Harokopio University, Greece Reviewed by Marie-Joelle Franoise Virolle, Centre National de la Recherche Scientifique (CNRS), France Peng Li, Northwestern Polytechnical University, China Updates Copyright 2026 Niu, Wang, Lu and Yu