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In glaucoma, the progressive deterioration of the optic nerve is caused by loss of a specific neuronal population known as retinal ganglion cells (RGC), such that the condition has been classified as a neurodegenerative disease (85)

Although some evidence suggests variability, particularly in obese male patients, the majority of studies show that the stimulation of whole-body protein synthesis during hyperinsulinemia appears to be normal in T2DM subjects (64)

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