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3c) are expected to be less susceptible and able to strongly induce defences during biotic attack as demonstrated using MeJA treatment (Zhao et al

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For multi-route studies: Document diluent composition, pH, and concentration for each route

Similarly, trametinib (a MEK inhibitor) enhances the transcription of ferritin heavy chain (FTH1) and ferritin light chain (FTL) and promotes ferritinophagy through NCOA4 while reducing ferroportin expression, thereby increasing intracellular iron levels and ultimately triggering ferroptosis in PDAC cells [22]