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Indeed, the astrocyte activation and the glial scar formation were inhibited in a spinal cord injury (SCI) animal model transplanted with mesenchymal stem cells (MSCs) over-expressing HGF (Jeong et al., 2012)

Hortells, L., Johansen, A

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Mandatory USP Standards : The United States Pharmacopeia is developing monographs for commonly compounded peptides

Reported side effects Mild local irritation or discomfort at the injection site Headache (typically mild and short-lived) Nausea or dizziness in some patients Sweating Mild fever more commonly reported in post-stroke use, generally manageable with standard antipyretics Contraindications Cerebrolysin is not recommended for individuals with: Active epilepsy or seizure disorders Severe renal (kidney) impairment Known hypersensitivity to any component of the formulation Note: A 2023 Cochrane review noted a potentially higher rate of spontaneous adverse events in some stroke trial subgroups