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The following serious adverse reactions are discussed elsewhere in the labeling: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed cannot be directly compared to rates in other clinical trials and may not reflect the rates observed in practice

The R5P is subsequently converted to PRPP with the assistance of PRS and further transformed into NMN by NAMPT (Shoji et al., 2021)

Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis

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