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33 Advances in specific microfluid cell culture systems (e.g., microfabricated fluid channels and microfabricated blood vessel systems) will provide new insights into the cellular mechanisms of arterial stiffness

& Van Damme, J

Scherrer, U

* For sustainable weight management, focus on small, achievable goals, cultivate a support network, and discuss treatment options with a healthcare provider

For patients whose clinical situation requires moderate rather than maximal weight loss, such as those with early-stage metabolic dysfunction where 10-12% weight loss is sufficient to normalize metabolic parameters, orforglipron's efficacy profile may be adequate and its oral convenience advantageous