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10.14309/ajg.0000000000000072 115

Intestinal microbiota in health and disease

Immune modulator The immune system is dedicated to protect organisms from harmful substances, and IL-2, as an important immune modulator, plays a crucial role in T-cell development and expansion, and has been approved by the FDA as an antitumor drug for patients with renal cell carcinoma (RCC) and melanoma

For the GSSG estimation, 100 L of the supernatant was mixed with 900 L of reaction buffer containing NADPH (nicotinamide adenine dinucleotide phosphate, reduced form, 0.3 mM) and GR (30 U mL 1 ) and incubated at room temperature for 30 min