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Headache: Headaches are a less common side effect of vitamin B12 injections but can occur in some individuals

Some medications also reduce B12 absorption (Sobczyska-Malefora et al., 2021) among the main ones are: metformin, proton pump inhibitors (PPIs), such as omeprazole, lansoprazole and esomeprazole, and H2-receptor antagonists, such as ranitidine, cimetidine, famotidine and nizatidine

"Microbial production of vitamin B 12 by methanol utilizing strain of Pseudomonas species"

Because it is inexpensive to source, the margin sits in the programme, not the vial another reason to build MIC into supervised care rather than sell it as a standalone product

However, further studies are still needed to optimize its clinical application, including dosage form improvement, combination therapy strategies and long-term safety assessment