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Dysfunction of SLC7A11 has been reported in diverse types of cancer, including PC, and is closely related to the malignant behavior of cancer [31, 32]

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Loss of LLF GGT activity in the mutant GGT enu1 mouse causes an increase in baseline LLF glutathione content which is magnified in an IL-13 model of allergic airway inflammation and protective against asthma

A study where healthy individuals received a -HB infusion to achieve a concentration of approximately 5.5 mmol/L demonstrated a 14% reduction in brain glucose utilization and a significant 30% increase in cerebral blood flow, with unchanged oxygen consumption [77]