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Statistical analyses The MannWhitney test or Welch's t-test was used to assess the statistical significance of differences between values for data collected from all assays

Similarly, in Van + XAV939 rats, there was a significant 61.1% decrease in the p-GSK-3/t-GSK-3 ratio relative to the XAV939-free Van group

Different from GSH-TPGS, GSH-PEG employed GSHs thiol group ( S -terminal) for linkage to PEG to form a thioether bond instead of an ester bond derived from the C -terminal linkage of the glycine carboxylic acid in GSH-TPGS

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