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Moreover, in mouse model of dextran sulfate sodium colitis treated with NPY antisense oligonucleotides, researchers observed decreased TNF- levels and reduced NF-B phosphorylation 15

It may help with flu, chronic bronchitis, and COPD symptoms, but the evidence is weak for its purported ability to thin mucus during a cold and for general claims of "immune support." Very preliminary studies suggest benefits for polycystic ovary syndrome (PCOS), Sjogren's syndrome, schizophrenia, compulsive behavior, and anti-aging

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2,3 This is of importance because the gut microbiota fulfills many critical roles in essential host functions such as protection against pathogens, immune-system modulation, fermentation of non-digestible dietary fibres, anaerobic metabolism of peptides and proteins, interaction with the hosts circadian clock and biotransformation of xenobiotics