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Tomita S, Sekiguchi F, Deguchi T, Miyazaki T, Ikeda Y, Tsubota M, et al

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Toxicity of polymeric nanoparticles in vivo and in vitro

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4.4 Targeting mitochondria autophagy to increase tumor immunity Mitochondrial autophagy, as a core mechanism regulating mitochondrial homeostasis, exerts bidirectional effects in tumor immunity by influencing immune cell function, tumor microenvironment metabolism, and innate immune pathways: It can maintain effector function by clearing damaged mitochondria from immune cells and enhance immune responses by activating the STING pathway