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Reduced DHFR activity is relatively uncommon in European populations but considerably more prevalent in some Asian populations

Objectives The objective of the current study was to use magnetic resonance spectroscopy (MRS) to measure cortical GSH levels in young people with bipolar disorder to determine if lowered GSH might be a useful biomarker of vulnerability to the illness

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Toxicol Sci 63:5764 Kavian N, Mehlal S, Marut W, Servettaz A, Giessner C, Bourges C, Nicco C, Chreau C, Lemarchal H, Dutilh MF, Cerles O, Guilpain P, Vuiblet V, Chouzenoux S, Galland F, Quere I, Weill B, Naquet P, Batteux F (2016) Imbalance of the vanin-1 pathway in systemic sclerosis

Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia