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Nrf2 is known to induce many antioxidant enzymes via the antioxidant response element in their promoters, including enzymes involved in the synthesis and metabolism of glutathione

the surplus is excreted

It is known to induce CYP2E1 activity by protein stabilization (18)

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FIGURE 6 3.3.1 Curcumins function in microRNA control Curcumin influences the transcription and stability of miRNAs by upregulating tumor-suppressive miRNAs and downregulating oncomiRs, alters the expression of lncRNAs such as Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) and Urothelial Carcinoma-Associated 1(UCA1), and modifies the networks of circRNAs, specifically the miRNA sponging axes