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Probiotics may favor virus clearance by enhancing immune function, inhibiting the activation of NLRP3 inflammasome (Synodinou et al., 2022), protecting the gut barrier, and preventing the co-infection of COVID-19 related bacteria (Patra et al., 2021

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Studies have reported OCTN2 expression in respiratory epithelial cells and alveolar macrophages, which is especially high in the upper lung region [301], and OCTN2-mediated carnitine uptake plays an important role in maintaining respiratory cilia beating and airway mucociliary clearance function, helping to remove excess mucus and potentially harmful substances from the airway [302]