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doi: 10.1210/me.2004-0115

Although both chronologic age and comorbidities may be considered surrogates of functional reserve, their accurateness as single parameters in defining a patient overall well-being is limited

Boggiano C, Eichelberg K, Ramachandra L, Shea J, Ramakrishnan L, Behar S, Ernst JD, Porcelli SA, Maeurer M, Kornfeld H (2017) The Impact of Mycobacterium tuberculosis Immune evasion on protective immunity: implications for TB vaccine design - meeting report

JHU083 has also demonstrated excellent therapeutic efficacy in preclinical models of IDH-mutant gliomas and significantly reduces mTOR signaling (Yamashita et al., 2021)