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They hadn't had patients who reported long-term symptoms, but said that if the symptoms occurred very quickly after vaccination, they could be related to allergic reactions or presyncope.April 27: Doctors suggested that patients with a history of immune-mediated thrombocytopenia, such as heparin-induced thrombocytopenia, should not get the Johnson and Johnson vaccine (mRNA vaccines like Pfizer and Moderna are ok)

Both have their pros and cons

The effect of Berberine on weight loss in order to prevent obesity: A systematic review

Its also approved for people who are obese, defined by a BMI of 30 or greater, and are looking for a treatment to aid in weight management