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Several conditions underlie OS in obesity, including hyperglycemia, hyperlipidemia, chronic inflammation, and inadequate antioxidant defenses, which are closely linked, although some contribute more than others

Cheng, X

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Benitez LV, Allison WS

Additionally, the interaction between alpha-synuclein and phospholipids in cell membranes can generate ROS, further exacerbating oxidative damage and neuronal dysfunction [163]