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The use of tofacitinib significantly reduced the type I IFN gene signature, levels of LDNs and circulating NETs, which consequently ameliorated SLE and its associated vascular dysfunction (167)

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Chen R, Wu X, Jiang L, Zhang Y

Administer a GHRP during a high-somatostatin window and the GH response is blunted exactly what the physiology predicts from a compound that respects normal secretory architecture