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Estrogen and progesterone have protective effects on renal blood flow, glomerular filtration rate, and ion and water reabsorption, while testosterone tends to impair these functions 54

We do not believe that it would be typical to perform tasks such as Greeting/gowning the patient (CA009), Obtain vital signs (CA010), or Provide education/obtain consent (CA011) in the vascular ultrasound room, some or all of which would need to take if the survey times submitted by the commenter were to be true

This is a genuine gap in the safety dossier, not a minor technicality

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Individual GH-releasing peptides cause mild water retention in some users