napqi glutathione mechanism File:Acetaminophen metabolism.jpg Solved The following figure shows
Solved The following figure shows the metabolism of the Metabolic pathway for NAPQI formation and detoxification by conjugation Download Scientific Diagram 3 Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non toxic byproducts (cysteine + mercapturic acid) that are excreted. Example: Glutathione is your liver's safety net against toxins. Fasting depletes Glutathione, turning "safe" Paracetamol doses into a liver toxic emergency. Don't let a therapeutic dose become a lethal one. See the safety protocols on BMJ Best Practice via bio. #MedEd # PharmGKB summary: Pathways of acetaminophen metabolism at the therapeutic versus toxic doses PMC
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