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The PCR products were purified, digested with XhoI and BamHI, and cloned into pLG669z (Guarente and Ptashne, 1981)

N Engl J Med 334(22):14481460 Topal G, Brunet A, Millanvoye E, Boucher J, Rendu F, Devynck M, David-Dufilho M (2004) Homocysteine induces oxidative stress by uncoupling of NO synthase activity through reduction of tetrahydrobiopterin

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