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The American Heart Association therefore recommends the consumption of food rich in antioxidant vitamins and other nutrients, but does not recommend the use of vitamin E supplements to prevent cardiovascular disease

Nowadays, the discovery of CFTR modulators that aim to increase or potentially restore the function of the disease-causing CFTR protein (Lopes-Pacheco, 2016) as well as the development of gene therapy have provided new opportunities to treat CF (Perry et al., 2017)

Elevated intraocular pressure increases melatonin levels in the aqueous humour

Furthermore, itaconate inhibits M2 macrophages polarization by inhibiting JAK1 and STAT6 phosphorylation (138)

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