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p53 mediation of these metabolic adaptations to acidosis appears to play an important role in cellular proliferation, as p53-deficient cells also have dramatically reduced cellular proliferation under acidosis (Figure 5H)

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Dosing ALCAR ALCAR is approved by the FDA for the treatment of certain LC deficiency syndromes

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The role of the ER stress-response protein PERK in rhodopsin retinitis pigmentosa