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Cancer 24 (1), 13

Subsequently, 1 ml of identical medium was added to the lower compartment

Likewise, mood stabilizers detected in the blood of patients with bipolar disorders have been related to decelerated aging using an epigenetic clock [11], and this class of drugs (including lithium carbonate, sodium valproate, and carbamazepine) can extend lifespan and/or healthspan in model organisms [12,13,14]

Achyranthes bidentum polysaccharide has vital anti-inflammatory and antalgic effects, and can promote chondrocyte proliferation and suppress chondrocyte apoptosis [117]

Our results uncover a new noncanonical function of PKM2 as a transcriptional coactivator of Nrf2, which cooperates with its metabolic function to divert glucose flux into the pentose phosphate pathway 55 and thereby generates sufficient GSH for ROS detoxification