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They secrete a spectrum of profibrotic mediators, including TGF-1, IL-10, arginase-1, and CCL18, which promote fibroblast proliferation, myofibroblast differentiation, and excessive ECM deposition (109)

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Butyrate inhibits histone deacetylase 2 expression to alleviate liver fibrosis in biliary atresia

These receptors allow the muscle to utilize testosterone resulting in an enhanced ability to build muscle