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This increase in fission, however, has a protective effect in this context because it sensitizes ectopic endometrial cells to apoptosis by promoting release and activation of the mitochondrial serine protease HtrA2/Omi, which cleaves and inactivates inhibitor-of-apoptosis proteins (IAPs), thereby weakening a major anti-apoptotic defense and reducing lesion invasion and migration ( 4.3 Mitochondrial autophagy and endometriosis Mitochondrial autophagy, or mitophagy, is a highly selective, damage-responsive clearance process that identifies, labels, and removes dysfunctional, depolarized, or aged mitochondria while preserving the healthy mitochondrial network

For the primary CosMx experiment, 22 FOV were selected, five were ultimately eliminated due to poor tissue adherence or low gene count per cell

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ESR was mildly elevated by about 3mm/hr above the upper limit of normal

It belongs in a comparison page where the details that matter most are access, cost, clinical fit, and what a licensed clinician should confirm