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The absence of signal could reflect genuine safety, or it could reflect the absence of a system designed to detect the signal

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[sources 7] These findings were subsequently corroborated by a 2022 meta-analysis that sampled nearly four million participants, which found no association between therapeutic use of amphetamine and the development of cardiovascular disease in any age group

10.1523/JNEUROSCI.0295-20.2020 J

even small temperature excursions accumulate across weeks of active use, and careful logging makes it straightforward to correlate experimental drift with material handling