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Finally, JNJ-7706621 is a dual inhibitor of the Ser/Thr cyclin dependent kinases (CDK1 and CDK2) and Aurora kinases, with IC 50 's in the 3250 nM range 49

its ability to reduce inflammation and improve tissue repair can contribute to reducing the pain and discomfort associated with an injury or post-op pain

Biomed Pharmacother 144:112271 Khassafi N, Azami Tameh A, Mirzaei H, Rafat A, Barati S, Khassafi N et al (2024) Crosstalk between Nrf2 signaling pathway and inflammation in ischemic stroke: mechanisms of action and therapeutic implications

This study contains several limitations

For longer storage, some researchers freeze aliquots at -20 degrees Celsius, though repeated freeze-thaw cycles degrade peptides