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All protocol-level guidance is based on published data and preclinical evidence cited inline

Theprincipal distinction between methyl-, ethyl-, andn-propyl-cobalamin lies in the relative stability of this MLCT state, with the terminal alkyl groups in ethyl and n-propyl acting as electron donors to destabilize the partial carbon anion in the MLCT state

Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A 1 and A 2A adenosine receptors and PI3K, MEK, and PKC pathways

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