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Inflammation 40 (5), 14751486
Funding This work was supported by the Natural Science Foundation of Hebei Province (C2022205026), the Foundation of Hebei Normal University (L2023T05), and the National Natural Science Foundation of China (31472050)
It arises from an abnormally expanded CAG trinucleotide repeat encoding the elongated polyglutamine (polyQ) within exon 1 of Huntingtin ( HTT ) gene, which results in the production of toxic mutant huntingtin proteins (mHTT) that accumulate in neurons, particularly in the striatum and cortex (Genetic Modifiers of Huntingtons Disease Consortium, 2019)
Were excited about this study because it has the possibility for Tivic to expand our non-invasive bioelectronic solutions from trigeminal and sympathetic nerve stimulation to vagus nerve pathways and clinical uses
