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at 14th day (Figure 10k) prominent proliferation and maturation of collagen fibers type 1

Their studied mechanisms are complementary: one is examined for vascular and cytoprotective signaling and the other for cytoskeletal and migratory dynamics

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This decline leads to insufficient activation of sirtuins (SIRT1SIRT7)NAD+-dependent deacetylases that regulate mitochondrial biogenesis via PGC-1, DNA repair, and cellular stress resistance