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Patients who are pregnant or breastfeeding, patients with active malignancy, patients with certain vascular conditions where angiogenesis is a concern, and patients on specific anticoagulants may not be candidates

For topical use, transient local reactions redness, stinging, burning, or itch are the expected category and are exactly what the ongoing Phase 2 trial is set up to measure (NCT07437586)

Researchers investigating DSIPs interaction with stress-response pathways may also find it of interest alongside peptides like Selank, which has its own preclinical record in anxiety-related animal models, and Epitalon, which has been studied in aging and antioxidant contexts

Quality of life: Energy levels 4/10 8/10, sleep quality 5/10 9/10, libido 3/10 8/10, mood scores (depression 8 2, anxiety 7 3), life satisfaction dramatically elevated

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